Endocrine Abstracts

Objective: Melatonin is a hormone secreted by the pineal gland which modulates sleep and wakefulness rhythms. Decreased melatonin secretion has been shown to be associated with increased daytime sleepiness and disturbed circadian rhythm in (irradiated) survivors of childhood craniopharyngeoma. The present study was performed to explore possible relationships between disturbed sleep, psychosocial impairment and melatonin secretion in patients treated with cranial radiotherapy a...

Objective: Brain tumour treatment with radio- and chemotherapy may lead to endocrine and other medical sequelae. Still, many countries lack tailored surveillance programs for such patients so that potential health problems may remain unrecognized. The present study was performed to investigate endocrine and psychosocial impairment in a single centre university setting in Germany in patients treated with cranial radiotherapy as a part of brain tumour or leukaemia treatment....